Lamivudinbehandling af en hepatitis Bs- antigen-positiv patient med reaktiv artritis
Engelsk titel: Lamivudine treatment of a hepatitis Bs antigen positive man with reactive arthritis
Läs online
Författare:
Borup C
;
Siboni A
Email: anders.siboni@shs.regionsyddanmark.dk
Språk: Dan
Antal referenser: 4
Dokumenttyp:
Fallbeskrivning
UI-nummer: 09011644
Sammanfattning
A 46-year-old man who was HBs antigen positive since childhood had painful talocrural arthritis that was considered re-active to HBs antigen. Lamivudine treatment was started and HBV-DNA disappeared from the blood, and the joint swellings disappeared. HBe antibody disappeared after eight months. After one year and nine months lamivudine was discontinued, resulting in a flare of the hepatitis after 56 days: HBV-DNA rose to 40 million copies per ml and HBe antigen became positive. Lamivudine was reinstituted, resulting in normalization of ALAT and lowering of HBV-DNA under detection level.