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Polyarteritis nodosa og hepatitis B-infektion behandlet med lamivudin
Engelsk titel: Polyarteritis nodosa and hepatitis B infection treated with lamivudine Läs online Författare: Munster T ; Weis NM ; Krogsgaard K Språk: Dan Antal referenser: 6 Dokumenttyp: Fallbeskrivning UI-nummer: 02011668

Tidskrift

Ugeskrift for Laeger 2002;164(3)342-3 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

A 36-year-old man was diagnosed with polyarteritis nodosa (PAN). He presented with weight loss, hypertension, and mono-neuritis. Pneumoperitoneum and septicaemia developed and laparotomy revealed necrosis of a segment of the ileum. The patient was HBsAg/HBeAg and HBV DNA positive. Liver biopsy showed active cirrhosis. The PAN symptoms remitted upon treatment with prednisolone and lamivudine. Seroconversion from HBeAg to anti-HBe occurred six months later. One year after the end of treatment, the patient was still HBeAg and HBV DNA negative, with normal liver enzymes and no symptoms of PAN.