Engelsk titel: Early identification and treatment of cardiovascular failure in severe sepsis
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Författare:
Haase N
;
White J
;
Perner A
Email: nicolai.haase@regionh.com
Språk: Dan
Antal referenser: 20
Dokumenttyp:
Översikt
UI-nummer: 10011283
Sammanfattning
Severe sepsis is a leading cause of death characterised by infection-induced endothelial and cardiac dysfunction leading to hypovolaemia, maldistribution of flow, tissue ischaemia and organ failure. A clinical approach with focus on cardiovascular diagnostics and rational goal-directed therapy is likely to reduce the high mortality. The treatment involves focus control, broad-spectrum antibiotics, target-oriented fluid therapy and vasopressor and inotropic agents guided by frequent reassessments of the patient's response to treatment.