Engelsk titel: Low prevalence of Mycoplasma genitalium in patients examined for Chlamydia trachomatis
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Författare:
Nilsen, Einar
;
Vik, Einar
;
Reed, Marie Aslaksen
Email: einar.nilsen@unn.no
Språk: Nor
Antal referenser: 21
Dokumenttyp:
Artikel
UI-nummer: 11111274
Sammanfattning
Background. There is increasing interest in Mycoplasma genitalium as a sexually transmissible pathogen. The clinical picture resembles that of Chlamydia trachomatis infection, but the natural course has not been well defined. There are no national guidelines regarding who should be examined for M. genitalium. Most of the prevalence studies have been carried out in patients attending clinics for sexually transmissible diseases. We have examined the prevalence in samples sent from general practice questioning the diagnosis C. trachomatis.
Material and method. During the period 1 October to 31 December 2010, all the samples sent to Molde Hospital that queried C. trachomatis were examined. Both agents were examined using real time PCR. The PCR for C. trachomatis was performed using a CE labelled and IVD approved method from Roche. The PCR for M. genitalium was performed using an in-house method where the target gene is GAP.
Result. A total of 950 patients were examined (Men n=225, women n=725). The prevalences of M. genitalium and C. trachomatis were 2.0?% and 10.0?% respectively (men 4.0?% and 15.1?%, women 1.4?% and 8.4?%).
Conclusion. Because of the low prevalence, we recommend selection of patients for examination for M. genitalium. The difference in prevalence between the sexes can reflect different indications for sample taking.