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Hereditärt angioödem - svår sjukdom med nya terapialternativ
Engelsk titel: Hereditary angioedema - difficult disease with new therapeutic options Läs online Författare: Björkander, Janne ; Bygum, Anette ; Waage Nielsen, Erik Språk: Swe Antal referenser: 60 Dokumenttyp: Översikt UI-nummer: 12017769

Tidskrift

Läkartidningen 2012;109(3)99-103 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

We review the pathophysiology, clinical presentation and treatment of hereditary angioedema in Sweden, Denmark and Norway. Different treatments with C1-inhibitors, androgens, anti-fibrinolytics as well as bradykinin and kallikrein inhibitors are suggested and the mechanisms behind. We also describe the treatment of children as well as special aspects of treatment during pregnancy and lactation. An extensive analysis of the literature, with emphasis on international consensus reports, shows a huge number of recent scientific reports.