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Malign ovarietumor som årsag til virilisering af en 12-årig pige
Engelsk titel: Malignant ovarian tumour as cause of virilisation in a 12 year-old girl Läs online Författare: Vestergård Andersen, Dorthe ; Northman Hermansen, Mette Språk: Dan Antal referenser: 4 Dokumenttyp: Fallbeskrivning UI-nummer: 12047908

Tidskrift

Ugeskrift for Laeger 2012;174(16)1095-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Virilisation in girls includes androgen dependent growth of terminal hair, acne, deepening of the voice and increased muscle mass. Sudden onset of symptoms, rapid progression, short duration and hyperandrogenemia are ominous signs and the patient must be referred to a specialist as soon as possible to rule out cancer and avoid worsening of the irreversible virilisation. We describe a girl with severe virilisation as the sole symptom of an androgen producing Sertoli-Leydig cell tumour. Ovarian tumours are rare in children and malignant ovarian tumours account for less than 1% of childhood cancer.