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Statiner ved akut koronart syndrom - en gennemgang af et Cochranereview
Engelsk titel: Early administration of statins after acute coronary syndrome Läs online Författare: Linde, Jesper James ; Boje Jensen, Gorm Språk: Dan Antal referenser: 10 Dokumenttyp: Artikel UI-nummer: 12077170

Tidskrift

Ugeskrift for Laeger 2012;174(26-33)1801-3 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

In this Cochrane review the potential benefits and harms of early administrations of statins after acute coronary syndrome (ACS) were evaluated in 18 randomized trials including 14,303 patients. No statistically significant effect was found on the primary combined outcome of death, myocardial infarction and stroke, but at four-month follow-up the incidence of unstable angina pectoris was significantly reduced. Despite the lack of evidence for an additional effect of early statin administrations on hard clinical end points, we find good reasons to maintain statins in the early treatment of ACS.