Sök artiklar i SveMed+

Observera: SveMed+ upphör att uppdateras!



Osteonekrose i kaeberne - en alvorlig bivirkning til antiresorptiv behandling
Engelsk titel: Osteonecrosis of the jaws. A severe complication to anti-resorptive treatment Läs online Författare: Schiödt, Morten Språk: Dan Antal referenser: 51 Dokumenttyp: Artikel UI-nummer: 15033416

Tidskrift

Aktuel Nordisk Odontologi 2015;40(1)61-95 ISSN 1902-3545 E-ISSN 2058-7538 KIBs bestånd av denna tidskrift

Sammanfattning

Osteonecrosis of the jaws (ONJ), in layman’s terms "dead bone" or "dead jaw", is a severe complication to anti-resorptive treatment with bisphosphonate, denosumab, and certain chemotherapeutic drugs. These drugs are used against osteoporosis and various malignant conditions (breast cancer, prostate cancer, multiple myeloma) with metastases in the skeleton. ONJ can cause pain, loss of teeth and parts of the jaws, and loss of masticatory function. Thus, ONJ is a severe cancer related complication, or ostoporosis treatment complication. ONJ was first reported in 2003, and during the last 10 year, a large number of cases have been reported worldwide.