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Engelsk titel: Osteonecrosis of the jaws (ONJ) associated to antiresorptive treatment Läs online Författare: Larsson Wexell, Cecilia ; Kjellman, Anders ; Akre, Olof Språk: Swe Antal referenser: 13 Dokumenttyp: Översikt UI-nummer: 18100097

Tidskrift

Läkartidningen 2018;115(22-23)976-8 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Osteonecrosis of the jaws (ONJ) has been associated to antiresorptive treatment and is an increasing problem all over the world. ONJ is a severe adverse effect of antiresorptive treatment with bisphosphonate and denosumab used for treatment of osteoporosis, metastases from certain malignant conditions and as an adjuvant treatment in postmenopausal women with breast cancer, and of treatment with certain chemotherapeutic drugs. In this paper the epidemiology, symptoms, diagnostic features, clinical findings, and treatment are reviewed. Guidelines are presented for dental treatment, surgery and referral of patients on antiresorptive treatment.