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På taersklen til en ny epoke i behandling af kronisk hepatitis C-virusinfektion
Engelsk titel: On the brink of a new era in the treatment of chronic hepatitis C virus infection in Denmark Läs online Författare: Eiset, Andreas Halgreen ; Holm, Maibritt Provstgaard ; Leutscher, Peter Derek Christian Språk: Dan Antal referenser: 29 Dokumenttyp: Översikt UI-nummer: 15037920

Tidskrift

Ugeskrift for Laeger 2015;177(2)134-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Treatment of chronic hepatitis C virus (HCV) has for more than a decade been based upon use of pegylated interferon in combination with ribavirin. Sustained virologic response rates are in general at a moderate level and severe adverse effects are frequent. With the introduction of direct acting antivirals (DAA) we now face the possibility of interferon-free treatment with higher response rates and less severe adverse effects. However, the costs of the DAAs are high presenting an additional economical burden to the health sector calling for necessary priorities to be taken.