Engelsk titel: InterPregGen:genetic studies of pre-eclampsia in three continents
Läs online
Författare:
Morgan, Linda
;
Mcginnis, Ralph
;
Steinthorsdottir, Valgerdur
;
Svyatova, Gulnara
;
Zakhidova, Nodira
;
Lee, Wai Kwong
;
Iversen, Ann-Charlotte
;
Magnus, Per
;
Walker, James
;
Casas, Juan Pablo
;
Sultanov, Saidazim
;
Laivuori, Hannele
Email: linda.morgan@nottingham.ac.uk
Språk: Eng
Antal referenser: 40
Dokumenttyp:
Översikt
UI-nummer: 15043683
Sammanfattning
Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of
genetic
variants which predispose to pre-eclampsia demands large DNA collections from affected mothers
and
babies and controls, with reliable supporting phenotypic data. The InterPregGen study has
assembled a
consortium of researchers from Europe, Central Asia and South America with the aim of elucidating
the
genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative
venture, which has the potential to provide new insights into the causes of pre-eclampsia, and
provide a
rational basis for novel approaches to prevention and treatment.