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Dansk Kolinesterase Kartotek udreder patienter med forlaenget paralyse efter suxamethon og mivacurium
Engelsk titel: Danish Cholinesterase Research Unit diagnoses patients with prolonged paralysis after succinylcholine and mivacurium Läs online Författare: Zwicky Eskildsen, Katrine ; Gätke, Mona Ring Språk: Dan Antal referenser: 15 Dokumenttyp: Översikt UI-nummer: 15067303

Tidskrift

Ugeskrift for Laeger 2015;177(9)866-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The Danish Cholinesterase Research Unit (DCRU) is a nationwide unit for patients carrying mutations in the butyrylcholinesterase enzyme (BChE). BChE hydrolyzes the neuromuscular blocking drugs succinylcholine and mivacurium. Patients with mutations in the butyrylcholinesterase gene are at risk of experiencing a prolonged effect of the drugs, such as weakness or paralysis for hours. In order to diagnose the referred patients correctly, DCRU combines results such as BChE activity, genotyping, pedigree and clinical reactions to succinylcholine or mivacurium.