Dansk Kolinesterase Kartotek udreder patienter med forlaenget paralyse efter suxamethon og mivacurium
Engelsk titel: Danish Cholinesterase Research Unit diagnoses patients with prolonged paralysis after succinylcholine and mivacurium
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Författare:
Zwicky Eskildsen, Katrine
;
Gätke, Mona Ring
Email: k-eskildsen@hotmail.com
Språk: Dan
Antal referenser: 15
Dokumenttyp:
Översikt
UI-nummer: 15067303
Sammanfattning
The Danish Cholinesterase Research Unit (DCRU) is a nationwide unit for patients carrying mutations in the butyrylcholinesterase enzyme (BChE). BChE
hydrolyzes the neuromuscular blocking drugs succinylcholine and mivacurium. Patients with mutations in the butyrylcholinesterase gene are at risk of
experiencing a prolonged effect of the drugs, such as weakness or paralysis for hours. In order to diagnose the referred patients correctly, DCRU combines
results such as BChE activity, genotyping, pedigree and clinical reactions to succinylcholine or mivacurium.