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Faekal calprotectin er en klinisk anvendelig markör for intestinal inflammation
Engelsk titel: Faecal calprotectin is a useful biomarker for intestinal inflammation Läs online Författare: Theede, Klaus ; Kiszka-Kanowitz, Marianne ; Nordgaard-Lassen, Inge ; Mertz Nielsen, Anette Språk: Dan Antal referenser: 29 Dokumenttyp: Översikt UI-nummer: 15117800

Tidskrift

Ugeskrift for Laeger 2015;177(19)1813-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Faecal calprotectin is a biomarker for inflammation in the intestinal mucosa. Faecal calprotectin has the ability to detect inflammatory causes of gastrointestinal symptoms and to distinguish these from irritable bowel syndrome. The test is very sensitive but not specific to any particular gastrointestinal disease. In inflammatory bowel disease, faecal calprotectin correlates with symptoms, biochemical markers and the endoscopic findings. It can be used to monitor disease activity, treatment response and mucosal healing as well as predict relapse. We propose an algorithm for the use of faecal calprotectin in patients with unspecific abdominal complaints.