Zinc bioavailability in rats fed a plant-based diet: a study of fermentation and zinc
supplementation
Engelsk titel: Zinc bioavailability in rats fed a plant-based diet: a study of fermentation and zinc
supplementation
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Författare:
Lazarte, Claudia E
;
Vargas, Mirian
;
Granfeldt, Yvonne
Email: claudia_lazarte15@hotmail.com
Språk: Eng
Antal referenser: 39
Dokumenttyp:
Artikel
UI-nummer: 15123775
Sammanfattning
Background: Zinc deficiency is a significant problem, in developing countries and in
vegetarians, which can be
caused by plant-based diets. Thus, dietary strategies, such as fermentation, to improve zinc
bioavailability of
diets should be investigated.
Objective: To improve zinc bioavailability in a plant-based diet by the inclusion of fermented food.
Design: Cassava tubers were fermented and made to replace the unfermented cassava in a basal
plant-based
diet, and compared with plant-based diets with and without zinc supplement. The zinc bioavailability
of the
diets was evaluated in Wistar rats that were fed these diets for 28 days. The evaluation was for zinc
apparent
absorption (ZnAA), serum zinc levels, and zinc deposits in liver and femur; in addition, the feed
efficiency
ratio (FER) of the diets and femur weight (FW) of the rats were evaluated.
Results: During the cassava fermentation, lactic acid increased and pH decreased (from 6.8 to 3.9),
which
is favorable for native phytase activity, resulting in a 90.2% reduction of phytate content in cassava.
The
diet containing fermented cassava showed significantly higher levels of ZnAA, FER, and FW
(pB0.001).
Moreover, the zinc levels in serum and femur were significantly higher (pB0.001) compared with the
results of
the diet with unfermented cassava. The results clearly show a higher zinc bioavailability in the diet
containing
fermented cassava and are comparable with the results obtained with the plant-based diet with zinc
supplement.
Conclusions: In conclusion, the fermentation of cassava reduces the phytate content. The diet
containing the
fermented cassava represents a better nutritional alternative than the diet with unfermented cassava
and is
comparable with the zinc-supplemented diets.