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Kardiovaskulaere risici ved behandling med nonsteroide antiinflammatoriske laegemidler
Engelsk titel: Cardiovascular risks of non-steroidal anti-inflammatory drugs treatment Läs online Författare: Schmidt, Morten ; Fosböl, Emil Loldrup ; Torp-Pedersen, Christian ; Schjerning Olsen, Anne-Marie ; Christensen, Bo ; Gislason, Gunnar H Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 17030186

Tidskrift

Ugeskrift for Laeger 2017;179(4)314-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current evidence supports that all NSAIDs increase the risk of heart failure and elevate blood pressure, whereas the risk of thrombotic events varies with the type of drug. Use of newer selective cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardio­vascular safety of NSAIDs and presents recommendations for their use.