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Succesfuld behandling af svaer dabigatranoverdosering med idarucizumab hos en patient med nyresvigt
Engelsk titel: Successful treatment of severe dabigatran intoxication with idarucizumab in a patient with acute kidney injury Läs online Författare: Gjerlev Poulsen, Christina ; Bestle, Morten ; Boesby, Lene Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 17050306

Tidskrift

Ugeskrift for Laeger 2017;179(9)801-3 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.