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Immunterapi er kraeftbehandling med en helt ny bivirkningsprofil
Engelsk titel: Immunotherapy is cancer treatment with a novel side-effect profile Läs online Författare: Kondrup, Maria ; Raunkilde, Louise ; Svane, Inge Marie ; Schmidt, Henrik ; Bastholt, Lars Språk: Dan Antal referenser: 23 Dokumenttyp: Översikt UI-nummer: 18020332

Tidskrift

Ugeskrift for Laeger 2018;180(2)138-42 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Within the last few years we have treated still more types of cancer with immune checkpoint inhibitors – anti-cyto-toxic T-lymphocyte-associated-4 antibodies and anti-program­med cell death 1/anti-programmed cell death ligand 1 anti­bodies. A unique set of side effects called immune related adverse events irAEs may occur during treatment. Although severe irAEs remain rare they can become life-threatening. Early detection of irAEs and initiation of relevant treatment are therefore crucial to reduce the risk of long-term seque­lae. We provide a detailed overview of irAEs and recom­mendations for treatment according to established guidelines.