Kontrol og bekaempelse af dental biofilm
Sammanfattning
There is considerable research activity to discover new compounds and to explore new technologies and methods to kill and/or prevent the formation of dental biofilms. Antimicrobials and other treatments are used in dentistry to eliminate bacteria and bacterial biofilms. Antimicrobial compounds are incorporated into dental materials to inhibit biofilm formation. Antimicrobials are also used by patients for daily prevention of dental biofilm-associated diseases. The rationale for such use of antimicrobials is that the mechanical biofilm control is inadequate to prevent the development or progression of dental diseases. It is important to be aware that the daily use of antimicrobial substances may increase the selective pressure for resistance against the active substances and may lead to cross and co - resistance to other antimicrobial and antibiotic substances. Antimicrobials for daily prevention of dental biofilm-associated diseases should be limited and used only when mechanical cleaning and change in patient behavior is insufficient for disease control. This article gives a brief overview of antimicrobial compounds used for biofilm control and new technologies and strategies to combat dental biofilms.