Kontrol og bekaempelse af dental biofilm
Sammanfattning
There is considerable research activity to discover new com-
pounds and to explore new technologies and methods to kill and/
or prevent the formation of dental biofilms. Antimicrobials and
other treatments are used in dentistry to eliminate bacteria and
bacterial biofilms. Antimicrobial compounds are incorporated into
dental materials to inhibit biofilm formation. Antimicrobials are also
used by patients for daily prevention of dental biofilm-associated
diseases. The rationale for such use of antimicrobials is that the
mechanical biofilm control is inadequate to prevent the develop-
ment or progression of dental diseases. It is important to be aware
that the daily use of antimicrobial substances may increase the
selective pressure for resistance against the active substances and
may lead to cross and co-resistance to other antimicrobial and
antibiotic substances. Antimicrobials for daily prevention of dental
biofilm-associated diseases should be limited and used only when
mechanical cleaning and change in patient behaviour is insufficient
for disease control. This article gives a brief overview of antimicro-
bial compounds used for biofilm control and new technologies and
strategies to combat dental biofilms.