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Glukokortikoidinduceret diabetes og risikofaktorer under höjdosisbehandling
Engelsk titel: Glucocorticoid-induced diabetes and risk factors during high-dose therapy Läs online Författare: Pedersen-Bjergaard, Ulrik ; Schultz, Helga Holm ; Patel, Dustin Andersen ; Lommer Kristensen, Peter Språk: Dan Antal referenser: 23 Dokumenttyp: Översikt UI-nummer: 19030101

Tidskrift

Ugeskrift for Laeger 2018;180(24)2184-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

This review describes the cumulative incidence (CI) and risk factors of glucocorticoid (GC)-induced diabetes in patients commencing high-dose GC therapy: ≥ 30 mg prednisolone/day. Finally, methods of screening are discussed. In 13 studies, the CI of GC-induced diabetes ranges 12-65%, but with the current diagnostic criteria the CI is assessed to be 30-50%. Risk factors may include high age and high levels of BMI and glycated haemoglobin, respectively, before GC therapy. It is important to acknowledge, that hyperglycaemia in GC therapy is more prevalent postprandially, and screening should be planned accordingly.