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Fluorescensvejledt fjernelse af cerebrale glioblastomer
Engelsk titel: Fluorescence-guided resection of cerebral tumours Läs online Författare: Würgler Hansen, Rasmus ; Rom Poulsen, Frantz ; Schulz, Mette ; Bonde Pedersen, Christian Språk: Dan Antal referenser: 16 Dokumenttyp: Översikt UI-nummer: 19090043

Tidskrift

Ugeskrift for Laeger 2019;181(10)953-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Traditionally, cerebral tumours were operated through a microscope under white light. In recent years, MRI used for peroperative navigation and techniques of colour-visualising the malignant tissue have made resection more precise, radical and safe. However, 5-aminolevulinic acid has been shown to increase neurological deficit due to supramarginal resection. Two widely used substances for tumour-visualisation are 5-aminolevulinic and sodium fluorescein. Both have shown an increased rate of resection compared with white light, but the evidence towards 5-aminolevulinic acid is strongest.