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Cancerimmunterapi til behandling af haematologisk cancer
Engelsk titel: Cancer immune therapy for the treatment of haematological malignancies Läs online Författare: Holmström, Morten Orebo ; Klausen, Uffe ; Jörgensen, Nicolai Grönne ; Holmberg, Staffan ; Grauslund, Jacob ; Met, Özcan ; Svane, Inge Marie ; Möller Pedersen, Lars ; Knudsen, Lene Meldgaard ; Hasselbalch, Hans Carl ; Andersen, Mads Hald Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 20030096

Tidskrift

Ugeskrift for Laeger 2019;181(22)2126-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Cancer immune therapy is now used routinely for the treatment of several solid malignancies, albeit just recently having entered the clinic for treatment of haematological malignancies. Several studies demonstrate that cancer immune therapy is a promising treatment modality for the latter. Especially treatment with chimeric antigen receptor T cells for acute lymphoblastic leukaemia and lymphoma is promising. Other promising treatment modalities are immune check point inhibitors for both lymphoid and myeloid malignancies, as well as therapeutic cancer vaccination targeting tumour antigens.