Medikamentell sekundaerprofylakse etter transitorisk cerebral iskemi eller hjerneinfarkt
Engelsk titel: Drug therapy in secondary prophylaxis after transient cerebral ischemia or cerebral infarction
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Författare:
Salvesen R
Email: rolf.salvesen@nlsh.no
Språk: Nor
Antal referenser: 42
Dokumenttyp:
Översikt
UI-nummer: 03111724
Sammanfattning
BACKGROUND : Stroke is the third leading cause of death in western countries and the leading cause of dependence in activities of daily living. Efforts to reduce its prevalence should therefore be given the highest priority. Uncertainty prevails as to the significance of the various types of intervention.
METHODS : This review is based on personal experience, though mostly on a search for relevant literature in the Cochrane Library.
RESULTS : Important measures are treatment of hypertension with target area 140/90 mm Hg, anticoagulation in patients with atrial fibrillation and other potential sources of cardioemboli, and for the remainder antiplatelet agents in the form of acetylsalicylic acid, probably preferably combined with dipyradimole. One should also consider drugs reducing serum lipids.
INTERPRETATION : Adequate secondary prophylaxis after transient ischaemic attack (TIA) or ischaemic stroke is of potential great benefit in reducing the incidence of new stroke, myocardial infarction or premature vascular death. Standardised guidelines may facilitate implementation of these measures, if they are regularly updated and adjusted to the needs of the individual patient.