Engelsk titel: Dilated cardiomyopathy as a side effect of treatment with infliximab
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Författare:
Leetmaa TH
;
Markenvard JD
Email: busybee@get2net.dk
Språk: Dan
Antal referenser: 5
Dokumenttyp:
Fallbeskrivning
UI-nummer: 05091704
Sammanfattning
We report a case of heart failure after infusion of Remicade (infliximab) in a patient without heart insufficiency. The patient, a 25-year-old woman with inflammatory bowel disease, developed new-onset heart failure after receiving TNF antagonist therapy. After the treatment was discontinued and heart failure therapy was started, the patient improved significantly. The U.S. Food and Drug Administration has published 47 case reports of heart failure after therapy with a tumor necrosis factor antagonist, where 38 patients developed new-onset heart failure and 9 patients experienced heart failure exacerbation.There are no published reports of heart failure after TNF antagonist therapy in the Danish literature.