Engelsk titel: Genetic epidemiology - from gene to disease understanding
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Författare:
Andersen, Vibeke Charlotte
;
Vogel, Ulla
Email: Vibeke.andersen@viborg.rm.dk
Språk: Dan
Antal referenser: 10
Dokumenttyp:
Artikel
UI-nummer: 10021357
Sammanfattning
Both genetic and environmental factors contribute to the aetiology of many common diseases. Recently, progress has been made in the identification of susceptibility genes by candidate gene and genome-wide association studies. Thereby, a further molecular understanding of pathophysiological pathways has been obtained and the development of new therapeutic modalities based on rational drug design has been initiated. However, a host of methods and approaches are necessary to further increase the knowledge on the aetiology of the complex diseases.